Dyslipidaemia is the term used to describe any abnormal blood lipid or lipoprotein concentration. Hyperlipidaemia refers to any condition that elevates fasting triglyceride or cholesterol concentrations. Dyslipidaemia and hyperlipidaemia can be loosely categorised into four classes; hypercholesterolaemia, hypertriglyceridaemia, hyperlipoproteinaemia and hypolipoproteinaemia. The categorisation of dyslipidaemia and hyperlipidaemia depends on which blood lipid or lipoprotein is abnormal[1].
There are several causes for dyslipidaemias and hyperlipidaemias including genetic traits, co-morbidities (e.g. hypothyroidism, diabetes) and lifestyle factors which incorporate diet and activity levels[2].
Dyslipidaemia and hyperlipidaemia are treated through exercise, diet and pharmacotherapy interventions. The vast majority of literature agrees that the combination of exercise and diet lead to greater improvements in blood lipid profiles than the two interventions administered separately[3][4][5]. While pharmacotherapy is a common treatment for dyslipidaemia and hyperlipidaemia it falls outside the scope of this resource and as a result no in depth information will be presented on pharmacotherapy treatment.
^ Biggerstaff, K.D. & Wooten, J.S. 2008, "Hyperlipidemia and Dyslipidemia" in Clinical Exercise Physiology, eds. J.K. Ehrman, P.M. Gordon, P.S. Visich & S.J. Keteyian, 2nd edn, Human Kinetics, United States, pp. 247-264.
^ Biggerstaff, K.D. & Wooten, J.S. 2008, "Hyperlipidemia and Dyslipidemia" in Clinical Exercise Physiology, eds. J.K. Ehrman, P.M. Gordon, P.S. Visich & S.J. Keteyian, 2nd edn, Human Kinetics, United States, pp. 247-264.
^ Varady, K.A. & Jones, P.J.H. 2005, "Combination diet and exercise interventions for the treatment of dyslipidemia: an effective preliminary strategy to lower cholesterol levels?", The Journal of Nutrition, vol. 135, pp. 1829-1835.
^ Lalonde, L., Gray-Donald, K., Lowensteyn, I., Marchand, S., Dorais, M., Michaels, G., Llewellyn-Thomas, H.A., O’Connor, A., Grover, S.A. & The Canadian Collaborative Cardiac Assessment Group. 2002, "Comparing the Benefits of Diet and Exercise in the Treatment of Dyslipidaemia", Preventive Medicine, vol. 35, pp. 16-24.
^ Leon, A.S. & Sanchez, O.A. 2001, "Response of blood lipids to exercise training alone or combined with dietary intervention", Medicine & Science in Sports & Exercise, vol. 33, no. 6, pp. s502-s515.
Scope of Dyslipidaemia
Dyslipidaemia is the term used to describe any abnormal blood lipid or lipoprotein concentration. Hyperlipidaemia refers to any condition that elevates fasting triglyceride or cholesterol concentrations. Dyslipidaemia and hyperlipidaemia can be loosely categorised into four classes; hypercholesterolaemia, hypertriglyceridaemia, hyperlipoproteinaemia and hypolipoproteinaemia. The categorisation of dyslipidaemia and hyperlipidaemia depends on which blood lipid or lipoprotein is abnormal[1].
There are several causes for dyslipidaemias and hyperlipidaemias including genetic traits, co-morbidities (e.g. hypothyroidism, diabetes) and lifestyle factors which incorporate diet and activity levels[2].
Dyslipidaemia and hyperlipidaemia are treated through exercise, diet and pharmacotherapy interventions. The vast majority of literature agrees that the combination of exercise and diet lead to greater improvements in blood lipid profiles than the two interventions administered separately[3] [4] [5]. While pharmacotherapy is a common treatment for dyslipidaemia and hyperlipidaemia it falls outside the scope of this resource and as a result no in depth information will be presented on pharmacotherapy treatment.
Home